一群青少年打算趁著周末前往海边度假，却意外来到了一间偏僻的旅馆。迷路不打紧，更可怕的还在后头！一种神祕的性病迅速扩散，感染者全都成了欲火高涨的性爱狂魔四处找人爱爱！面对见人就上的感染者们，这群年轻人能否安然逃过被狂抽猛送的下场，度过这“屄”死人的夜晚？...

The film describes the events leading up to, and including, the massacre of the adults of a small town in Nebraska by their children, after the adults' irresponsibility ruins the crop and the children...